KẾT LUẬN VÀ ĐỀ XUẤT

46



ĐỀ XUẤT

Trên đây là một số công việc mà chúng tôi đã làm được trong thời gian qua .

Do thời gian có hạn nên chúng tôi chỉ khảo sát khía cạnh chính của đề tài.

Để phát triển và mở rộng khóa luận, chúng tôi có một số đề xuất sau:

-



Đánh giá độ ổn định của hệ tự nhũ hóa không chứa dược chất

chất và viên nén natri diclofenac giải phóng nhanh.



-



Nghiên cứu các biện pháp giảm khối lượng viên nén.



, chứa dược



TÀI LIỆU THAM KHẢO

Tài liệu tiếng Việt

1.



Thái Duy Thìn, Nguyễn Văn Thục (1998), Hóa dược, tập 1, NXB Y học, Hà

Nội, tr. 126.



2.



Bộ Y tế (2006), "Kỹ thuật bào chế và sinh dược học các dạng thuốc ", tập 2,

tr. 169-173.



3.



Bộ Y tế (2002), Dược thư quốc gia Việt Nam, tr. 371-374.



4.



Bộ Y tế Dược điển Việt Nam IV, NXB Y học, Hà Nội, tr. 226.



Tài liệu tiếng Anh

5.



Mahmoud E. A., Bendas E. R., Mohamed M. I. (2009), "Preparation and

evaluation



of



self-nanoemulsifying



tablets



of



carvedilol",



AAPS



PharmSciTech, 10(1), pp. 183-92.

6.



Mura P., Valleri M., Cirri M., Mennini N. (2012), "New solid selfmicroemulsifying systems to enhance dissolution rate of poorly water soluble

drugs", Pharm Dev Technol, 17(3), pp. 277-84.



7.



Rahman M. A., Hussain A., Hussain M. S., Mirza M. A., Iqbal Z. (2013),

"Role



of



excipients



in



successful



development



of



self-



emulsifying/microemulsifying drug delivery system (SEDDS/SMEDDS)",

Drug Dev Ind Pharm, 39(1), pp. 1-19.

8.



Aburahma Mona H, El-Laithy Hanan M, Hamza Yassin El-Said (2010),

"Oral



bioavailability



enhancement



of



vinpocetine



using



self-



microemulsifying drug delivery system containing long chain triglycerides:

Preparation and in vitro/in vivo evaluation", Clinical Research and

Regulatory Affairs, 27(4), pp. 97-107.

9.



Basalious Emad B, Shawky Nevine, Badr-Eldin Shaimaa M (2010),

"SNEDDS containing bioenhancers for improvement of dissolution and oral

absorption of lacidipine. I: Development and optimization", International

journal of pharmaceutics, 391(1), pp. 203-211.



10.



Bravo RH, USP NF (United States Pharmacopeia 32/National Formulary

27). 2009, United Book Press, Baltimore, Maryland.



11.



Committee Paediatric Formulary, BNF for children 2009. London: BMJ

Group. 2009, RPS Publishing and RCPCH Publications.



12.



Franceschinis E, Bortoletto C, Perissutti B, Dal Zotto M, Voinovich D,

Realdon N (2011), "Self-emulsifying pellets in a lab-scale high shear mixer:

Formulation and production design", Powder Technology, 207(1), pp. 113118.



13.



Kallakunta Venkata Raman, Bandari Suresh, Jukanti Raju, Veerareddy

Prabhakar Reddy (2012), "Oral self emulsifying powder of lercanidipine

hydrochloride: formulation and evaluation", Powder Technology, 221, pp.

375-382.



14.



Kang Myung Joo, Jung Soo Young, Song Woo Heon, Park Jun Sang, Choi

Sung-Up, Oh Kyung Taek, Choi Hyung-Kyoon, Choi Young Wook, Lee

Jaehwi, Lee Beom-Jin (2011), "Immediate release of ibuprofen from

Fujicalin®-based



fast-dissolving



self-emulsifying



tablets",



Drug



development and industrial pharmacy, 37(11), pp. 1298-1305.

15.



Khan Barkat Ali, Bakhsh Satar, Khan Haroon, Mahmood Tariq, Rasul

Akhtar (2012), "Basics of Self Micro Emulsifying Drug Delivery System",

Journal of Pharmacy and Alternative Medicine, 1, pp. 13-19.



16.



Kohli Kanchan, Chopra Sunny, Dhar Deepika, Arora Saurabh, Khar Roop K

(2010), "Self-emulsifying drug delivery systems: an approach to enhance

oral bioavailability", Drug discovery today, 15(21), pp. 958-965.



17.



Kommuru TR, Gurley B, Khan MA, Reddy IK (2001), "Self-emulsifying

drug delivery systems (SEDDS) of coenzyme Q< sub> 10:

formulation development and bioavailability assessment", International

journal of pharmaceutics, 212(2), pp. 233-246.



18.



Liu Wenli, Tian Rui, Hu Wenjing, Jia Yuntao, Jiang Huiming, Zhang

Jingqing, Zhang Liangke (2012), "Preparation and evaluation of self-



microemulsifying drug delivery system of baicalein", Fitoterapia, pp. 15321539.

19.



Milović Mladen, Djuriš Jelena, Djekić Ljiljana, Vasiljević Dragana, Ibrić

Svetlana



(2012),



"Characterization



and



evaluation



of



solid



self-



microemulsifying drug delivery systems with porous carriers as systems for

improved carbamazepine release", International journal of pharmaceutics.

20.



Mistry RAJAN B, Sheth Nirav S (2011), "A review: self emulsifying drug

delivery system", Int J Pharm & Pharm Sci, 3.



21.



Neslihan Gursoy R, Benita Simon (2004), "Self-emulsifying drug delivery

systems (SEDDS) for improved oral delivery of lipophilic drugs",

Biomedicine & Pharmacotherapy, 58(3), pp. 173-182.



22.



Patel Neelam D (2011), "An emerging technique for poorly soluble drugs:

self



emulsifying



drug



delivery



system",



International



Journal



of



Pharmaceutical & Biological Archive, 2(2).

23.



Pharmacopoeia British (2007), "CD-ROM, version 11", Data© Crown

Copyright.



24.



Porter Christopher JH, Pouton Colin W, Cuine Jean F, Charman William N

(2008), "Enhancing intestinal drug solubilisation using lipid-based delivery

systems", Advanced drug delivery reviews, 60(6), pp. 673-691.



25.



Qiu Yihong, Chen Yisheng, Zhang Geoff GZ, Liu Lirong, Porter William

(2009), Developing solid oral dosage forms: pharmaceutical theory &

practice, Academic Press.



26.



Raménkaya G .V Shokhin E. (2009), "modern approaches to quality

evaluation of generic drugs for their registration", pharmaceutical chemistry

Journal, 43 (9), pp. 30-34.



27.



Rowe Raymond C, Sheskey Paul J, Weller Paul J (2006), Handbook of

pharmaceutical excipients, Pharmaceutical press London, pp. 564-565.



28.



Sachan R, Khatri K, Kasture SB (2010), "Self-emulsifying drug delivery

system a novel approach for enhancement of bioavailability", Int J Pharm

Tech Res, 2(3), pp. 1738-1745.



29.



Sunitha R, Sireesha D Satya, Aparna MVL (2011), "Novel Self-emulsifying

Drug Delivery System-An approach to enhance bioavailability of poorly

water soluble drugs", International Journal of Research in Pharmacy and

Chemistry, 1(4), pp. 828-838.



30.



Tiwari R, Tiwari G, Rai AK (2010), "Self-emulsifying drug delivery system:

An approach to enhance solubility", Systematic Reviews in Pharmacy, 1(2),

pp. 133.



31.



Villar Ana Maria Sierra, Naveros Beatriz Clares, Campmany Ana Cristina

Calpena, Trenchs Monserrat Aróztegui, Rocabert Coloma Barbé, Bellowa

Lyda Halbaut (2012), "Design and optimization of self nanoemulsifying drug

delivery systems (SNEDDS) for enhanced dissolution of gemfibrozil",

International journal of pharmaceutics, pp. 161-175.